Introduction to designing, building, and training large-scale neural networks for modeling brain and behavioral data, including: deep convolutional neural network models of sensory systems (vision, audition, somatosensation); variational and generative methods for neural interpretation; recurrent neural networks for dynamics, memory and attention; interactive agent-based deep reinforcement learning for cognitive modeling; and methods and metrics for comparing such models to real-world neural data. Attention will be given both to established methods as well as cutting-edge techniques. Students will learn conceptual bases for deep neural network models and will also implement learn to implement and train large-scale models in Tensorflow using GPUs. Requirements: Fluency in Unix shell and Python programming; familiarity with differential equations, linear algebra, and probability theory; priori experience with modern machine learning concepts (e.g. CS229) and basic neural network training tools (eg. CS230 and/or CS231n). Prior knowledge of basic cognitive science or neuroscience not required but helpful.