Colloquium

Daniel Pine, MD, Chief, Section on Development and Affective Neuroscience in the National Institute of Mental Health (NIMH) Intramural Research Program

Title: Advancing Psychiatric Care Through Research in Clinical Neuroscience

Abstract: This presentation will review the ways in which research in neuroscience inform therapeutic discovery focusing on the area of mood and anxiety disorders. A developmental focus will be emphasized, highlighting perturbations in brain function that manifest similarly across ages as well as those that differ in pediatric and adult mood and anxiety disorders. The presentation will describe two specific approaches for attempting to develop novel therapeutics. One combines attention training with imaging and cognitive behavioral therapy in the treatment of anxiety disorders. The other attempts to tailor modular components of treatments to patient-specific needs while parsing heterogeneous presentations of depressive disorders.